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licH [2019-05-30 17:50:18]
6-phospho-beta-glucosidase
function
lichenan utilization
product
6-phospho-beta-glucosidase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.27|Utilization of other polymeric carbohydrates]Gene
Coordinates
3,958,516 3,959,844
The protein
Catalyzed reaction/ biological activity
6-phospho-beta-D-glucosyl-(1,4)-D-glucose + H2O = D-glucose + D-glucose 6-phosphate (according to Swiss-Prot)Protein family
glycosyl hydrolase 4 family (according to Swiss-Prot)Structure
[PDB|1S6Y] (Geobacillus stearothermophilus)Expression and Regulation
Operons
genes
[gene|65FC7F4ED92F747DB7BC5672DCA2D2320A471134|licB]-[gene|83A7C160B0301A2B51B65478D99ACB753D67AF74|licC]-[gene|E8B6C8E722BEE866878CDD816B7828C132F94FCD|licA]-[gene|84D8AA0AFBF46273F6B4198B49440D55470FEC0F|licH]
description
[Pubmed|8990303]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|8990303], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, [Pubmed|8990303], in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon][protein|E087ABA705CE94E2CAD44A0F2FB265B0F7B04399|LicR]: activation, [Pubmed|8990303], in [regulon|E087ABA705CE94E2CAD44A0F2FB265B0F7B04399|LicR regulon]regulation
carbon catabolite repression ([protein|search|CcpA]) [Pubmed|8990303]view in new tabBiological materials
Mutant
BKE38560 ([gene|84D8AA0AFBF46273F6B4198B49440D55470FEC0F|licH]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE38560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CGTTACAATCTTCAATCCTT, downstream forward: _UP4_TAAAAAAAGCCGGCCTGTAABKK38560 ([gene|84D8AA0AFBF46273F6B4198B49440D55470FEC0F|licH]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK38560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CGTTACAATCTTCAATCCTT, downstream forward: _UP4_TAAAAAAAGCCGGCCTGTAAReferences
19087206,8990303,16872404,10438772,8990303